Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5807507 | 0.99 | AAK1 (0.35) | KDM4EALDH1A1GAAMAPK1AAK1 | |
| SCHEMBL5810095 | 0.86 | MAPK1 (0.35) | KDM4EALDH1A1GAAMAPK1AAK1 | |
| Hydrochloric Acid SCHEMBL5811147 | 0.85 | MAPK1 (0.34) | KDM4EALDH1A1GAAMAPK1AAK1 | |
| SCHEMBL5806831 | 0.84 | MAOA (0.35) | KDM4EALDH1A1AAK1MAOAMEN1 | |
| SCHEMBL5809208 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPK1AAK1MAOAMEN1 | |
| Hydrochloric Acid SCHEMBL5805951 | 0.83 | MAOA (0.34) | KDM4EALDH1A1AAK1MAOAMEN1 | |
| SCHEMBL5806968 | 0.83 | DYRK1A (0.35) | KDM4EALDH1A1MAPK1AAK1MAOA | |
| Hydrochloric Acid SCHEMBL5806758 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MAPK1AAK1MAOAMEN1 | |
| Hydrochloric Acid SCHEMBL5806051 | 0.82 | DYRK1A (0.34) | ALDH1A1MAPK1AAK1MAOALMNA | |
| SCHEMBL5810011 | 0.81 | KMT2A (0.35) | KDM4EALDH1A1AAK1MAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |