SCHEMBL5810095

SCHEMBL5810095

Cc1c(C)n(C)c2c(OCCC(C)C)nccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
AAK1 Q2M2I8 4/20 0.33
CDK1 P06493 2/20 0.32
CCNB1 P14635 2/20 0.32
CCNA2 P20248 2/20 0.32
CDK2 P24941 2/20 0.32
CCNA1 P78396 2/20 0.32
HTT P42858 1/20 0.31
CYP19A1 P11511 1/20 0.31
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5811147 0.99 MAPK1 (0.34) MAPK1KDM4EALDH1A1GAAMAOA
SCHEMBL5807483 0.86 KDM4E (0.36) MAPK1KDM4EALDH1A1GAAMAOA
Hydrochloric Acid SCHEMBL5811037 0.85 ALDH1A1 (0.33) MAPK1ALDH1A1TDP1
SCHEMBL5810191 0.85 TDP1 (0.33) MAPK1KDM4EALDH1A1TDP1CDK1
Hydrochloric Acid SCHEMBL5807507 0.84 AAK1 (0.35) MAPK1KDM4EALDH1A1GAAMAOA
Hydrochloric Acid SCHEMBL5811743 0.84 TDP1 (0.32) KDM4EALDH1A1TDP1CDK1CCNB1
SCHEMBL5795382 0.83 AAK1 (0.35) MAPK1TDP1AAK1HTTCYP19A1
Hydrochloric Acid SCHEMBL5807412 0.83 ACSS2 (0.34) TDP1AAK1
Hydrochloric Acid SCHEMBL5809596 0.82 KMT2A (0.34) KDM4EALDH1A1AAK1
Hydrochloric Acid SCHEMBL5797553 0.82 AAK1 (0.35) KDM4EAAK1HTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed