Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719045 | 0.91 | METAP2 (0.48) | GRIK1FAAHCES1ANPEPERAP1 | |
| SCHEMBL3768499 | 0.91 | METAP2 (0.48) | GRIK1FAAHCES1ANPEPERAP1 | |
| SCHEMBL8599051 | 0.80 | FAAH (0.46) | GRIK1FAAHCES1MAOA | |
| SCHEMBL6556276 | 0.80 | EPHX1 (0.48) | MAOAANPEPCSNK1E | |
| SCHEMBL10622532 | 0.80 | EPHX1 (0.48) | MAOAANPEPCSNK1E | |
| Hydrochloric Acid SCHEMBL5711578 | 0.79 | EPHX1 (0.47) | MAOAANPEPCSNK1E | |
| SCHEMBL6024122 | 0.79 | GRIK1 (0.49) | GRIK1MAOAANPEPERAP1ERAP2 | |
| SCHEMBL14544283 | 0.77 | GRIK1 (0.54) | GRIK1MAOAANPEPERAP1ERAP2 | |
| SCHEMBL7998233 | 0.77 | GRIK1 (0.54) | GRIK1MAOAANPEPERAP1ERAP2 | |
| SCHEMBL456442 | 0.77 | GRIK1 (0.54) | GRIK1MAOAANPEPERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |