Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560746 | 0.92 | ELANE (0.37) | LMNAELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL5801018 | 0.91 | LMNA (0.38) | LMNAELANEADRB2ADRB1ADRB3 | |
| SCHEMBL5801021 | 0.91 | LMNA (0.38) | LMNAELANEADRB2ADRB1ADRB3 | |
| SCHEMBL5800314 | 0.89 | PTGS2 (0.32) | AKR1C3AKR1C2MEN1KMT2AALDH1A1 | |
| SCHEMBL5797107 | 0.88 | LMNA (0.40) | LMNAELANEADRB2ADRB1ADRB3 | |
| SCHEMBL5798904 | 0.88 | TSHR (0.35) | LMNATSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL5822046 | 0.87 | PTGS2 (0.39) | AKR1C3AKR1C2 | |
| SCHEMBL5796727 | 0.87 | LMNA (0.39) | LMNAELANEADRB2ADRB1ADRB3 | |
| SCHEMBL5796729 | 0.87 | LMNA (0.39) | LMNAELANEADRB2ADRB1ADRB3 | |
| SCHEMBL5799942 | 0.86 | LMNA (0.37) | LMNAELANEADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |