Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800314 | 0.91 | PTGS2 (0.32) | MGLLPTGS2KMT2AALDH1A1 | |
| SCHEMBL5822046 | 0.91 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL5799881 | 0.91 | TSHR (0.39) | TSHRMGLLLMNAPTGS2KMT2A | |
| SCHEMBL5799882 | 0.91 | TSHR (0.39) | TSHRMGLLLMNAPTGS2KMT2A | |
| SCHEMBL5797831 | 0.91 | PTGS2 (0.34) | TSHRLMNAPTGS2HPGD | |
| SCHEMBL5797833 | 0.91 | PTGS2 (0.34) | TSHRLMNAPTGS2HPGD | |
| SCHEMBL5560484 | 0.89 | TSHR (0.35) | TSHRMGLLSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5560746 | 0.89 | ELANE (0.37) | MGLLLMNAKMT2AALDH1A1HPGD | |
| SCHEMBL5797882 | 0.88 | PTGS2 (0.36) | TSHRSLC6A4SLC6A3LMNASLC6A2 | |
| SCHEMBL5797881 | 0.88 | PTGS2 (0.36) | TSHRSLC6A4SLC6A3LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |