SCHEMBL5807789

SCHEMBL5807789

COCN1CCOC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728747 0.88 PIK3CD (0.58)
SCHEMBL8722184 0.80 PIK3CD (0.41)
SCHEMBL791717 0.80 KDM4E (0.45)
SCHEMBL9550092 0.79 KDM4E (0.40)
SCHEMBL22146552 0.77 KDM4E (0.43)
SCHEMBL7001468 0.77 PIK3CD (0.39)
SCHEMBL11593071 0.77 PIK3CD (0.39)
SCHEMBL7276935 0.76 KDM4E (0.38)
SCHEMBL10961212 0.76 KDM4E (0.38)
SCHEMBL7276937 0.76 KDM4E (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006043121-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-27 WO claimed
EP-1210080-A2 USE OF MONOAMINE OXIDASE INHIBITORS FOR THE MANUFACTURE OF DRUGS INTENDED FOR THE TREATMENT OF OBESITY Sanofi-Aventis (FR) 2002-06-05 EP disclosed
WO-2001012176-A2 USE OF MONOAMINE OXIDASE INHIBITORS FOR THE MANUFACTURE OF DRUGS INTENDED FOR THE TREATMENT OF OBESITY SANOFI-SYNTHELABO (FR) 2001-02-22 WO disclosed
EP-0859776-A1 COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1998-08-26 EP disclosed
EP-0859775-A1 COMPOUNDS DERIVED FROM 3-(BENZOFURAN-5-YL)OXAZOLIDIN-2-ONE, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1998-08-26 EP disclosed
EP-0835254-A1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1998-04-15 EP disclosed
US-5716841-A Process for the resolution of ethyl 4,4,4-trifluoro-3(R)-hydroxybutanoate using lipase from candida SYNTHELABO (FR) 1998-02-10 US disclosed
WO-1997017346-A1 COMPOUNDS DERIVED FROM 3-(BENZOFURAN-5-YL)OXAZOLIDIN-2-ONE, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-05-15 WO disclosed
WO-1997017347-A1 COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-05-15 WO disclosed
WO-1996038444-A1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1996-12-05 WO disclosed
US-5171747-A Anxiolytic agents, antidepressants DELALANDE S.A. (FR) 1992-12-15 US disclosed
EP-0425209-A2 Naphthyloxazolidone derivatives TANABE SEIYAKU CO., LTD. (JP) 1991-05-02 EP disclosed