Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078130 | 0.83 | KDM4E (0.41) | PIK3CDKDM4ENQO2GRM2USP2 | |
| SCHEMBL5807789 | 0.77 | — | — | |
| SCHEMBL8722184 | 0.74 | PIK3CD (0.41) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL9550092 | 0.73 | KDM4E (0.40) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL11593071 | 0.71 | PIK3CD (0.39) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL10961212 | 0.70 | KDM4E (0.38) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL7276937 | 0.70 | KDM4E (0.38) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL7276935 | 0.70 | KDM4E (0.38) | PIK3CDKDM4ENQO2GRM2NAAA | |
| SCHEMBL261199 | 0.70 | — | — | |
| SCHEMBL21798023 | 0.69 | PRKCA (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001081350-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2001-11-01 | — | — | WO | disclosed |
| EP-0918770-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001447-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |
| US-4945182-A | TREATMENT OF GLAUCOMA | MERCK & CO., INC. (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0229507-B1 | OCULOSELECTIVE BETA BLOCKERS | MERCK & CO. INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0229507-A1 | Oculoselective beta blockers | MERCK & CO. INC. (US) | 1987-07-22 | — | — | EP | disclosed |