Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550092 | 0.84 | KDM4E (0.40) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL5807789 | 0.80 | — | — | |
| SCHEMBL10337323 | 0.79 | KDM4E (0.41) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL261199 | 0.77 | — | — | |
| SCHEMBL7001468 | 0.74 | PIK3CD (0.39) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL11593071 | 0.74 | PIK3CD (0.39) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL2781821 | 0.74 | — | — | |
| SCHEMBL7276935 | 0.73 | KDM4E (0.38) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL10961212 | 0.73 | KDM4E (0.38) | PIK3CDKDM4ENAAAGRM2NQO2 | |
| SCHEMBL7276937 | 0.73 | KDM4E (0.38) | PIK3CDKDM4ENAAAGRM2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859775-A1 | COMPOUNDS DERIVED FROM 3-(BENZOFURAN-5-YL)OXAZOLIDIN-2-ONE, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017346-A1 | COMPOUNDS DERIVED FROM 3-(BENZOFURAN-5-YL)OXAZOLIDIN-2-ONE, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |