Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822117 | 0.92 | EGLN1 (0.40) | EGLN1HRH3DHFRTRPC5 | |
| SCHEMBL5809821 | 0.91 | EGLN1 (0.40) | EGLN1HRH3DHFRKCNH2 | |
| SCHEMBL5810019 | 0.88 | EGLN1 (0.38) | EGLN1HRH3DHFR | |
| SCHEMBL5811720 | 0.86 | HRH3 (0.39) | EGLN1HRH3DHFRKCNH2 | |
| SCHEMBL5809686 | 0.86 | EGLN1 (0.39) | EGLN1HRH3DHFRUSP2ALDH1A1 | |
| SCHEMBL5811721 | 0.85 | HRH3 (0.42) | HRH3 | |
| SCHEMBL5214300 | 0.79 | HRH3 (0.37) | EGLN1HRH3KCNH2 | |
| SCHEMBL5166374 | 0.78 | ELANE (0.38) | EGLN1HRH3 | |
| SCHEMBL5812938 | 0.78 | EGLN1 (0.36) | EGLN1HRH3DHFRPTK2 | |
| SCHEMBL5810004 | 0.77 | EGLN1 (0.38) | EGLN1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | claimed |
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |