Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.33 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809686 | 0.88 | EGLN1 (0.39) | EGLN1MEN1POLBKMT2ADHFR | |
| SCHEMBL5809821 | 0.86 | EGLN1 (0.40) | EGLN1MEN1POLBKMT2ADHFR | |
| SCHEMBL5164538 | 0.86 | ELANE (0.36) | EGLN1DGAT1 | |
| SCHEMBL5811923 | 0.85 | DGAT1 (0.35) | EGLN1MEN1KMT2AGRM2DGAT1 | |
| SCHEMBL5738547 | 0.81 | MEN1 (0.39) | MEN1POLBKMT2AGRM2BRD4 | |
| SCHEMBL5740445 | 0.79 | MEN1 (0.44) | MEN1POLBKMT2ABRD4 | |
| SCHEMBL5807977 | 0.78 | EGLN1 (0.41) | EGLN1DHFRPTK2HRH3 | |
| SCHEMBL5737828 | 0.76 | NCF1 (0.35) | MEN1POLBKMT2ABRD4 | |
| SCHEMBL5822117 | 0.76 | EGLN1 (0.40) | EGLN1MEN1KMT2ADHFRGRM2 | |
| SCHEMBL5738194 | 0.76 | MEN1 (0.36) | MEN1POLBKMT2AGRM2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | claimed |
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |