SCHEMBL580807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1360468	0.87	TDP1 (0.44)	MEN1KMT2ALIPEALDH1A1TDP1
	SCHEMBL31395494	0.86	LIPE (0.42)	MEN1KMT2ALIPECYP3A4SMN1; SMN2
	SCHEMBL25426624	0.84	LIPE (0.55)	LIPEALDH1A1MAPT
	SCHEMBL25955360	0.83	LIPE (0.40)	MEN1KMT2ALIPEALDH1A1TDP1
	SCHEMBL25976343	0.83	LIPE (0.40)	MEN1KMT2ALIPEMAPT
	SCHEMBL25340238	0.83	LIPE (0.40)	MEN1KMT2ALIPEALDH1A1TDP1
	SCHEMBL30292561	0.79	APLNR (0.38)	LIPERAB9ATDP1
	SCHEMBL1484864	0.79	APLNR (0.38)	LIPERAB9ATDP1
	SCHEMBL22052722	0.79	LIPE (0.36)	MEN1KMT2ALIPE
	SCHEMBL29520838	0.78	NCOA1 (0.44)	MEN1KMT2AAPAF1LIPERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.