SCHEMBL25976343

SCHEMBL25976343

CC1(C)OB(c2cccnc2Oc2ccc(CF)cc2)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 5/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
UCHL1 P09936 1/20 0.36
P2RX3 P56373 4/20 0.35
DGAT1 O75907 1/20 0.35
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31395494 0.85 LIPE (0.42) LIPEMEN1KMT2A
SCHEMBL1360468 0.84 TDP1 (0.44) LIPEMEN1KMT2ADGAT1L3MBTL1
SCHEMBL25426624 0.83 LIPE (0.55) LIPEMAPT
SCHEMBL580807 0.83 MEN1 (0.45) LIPEMEN1KMT2AMAPT
SCHEMBL25340238 0.82 LIPE (0.40) LIPEMEN1KMT2AMAPT
SCHEMBL25955360 0.82 LIPE (0.40) LIPEMEN1KMT2AMAPT
SCHEMBL365301 0.79 L3MBTL1 (0.36) LIPEUCHL1L3MBTL1
SCHEMBL29900384 0.79 L3MBTL1 (0.36) LIPEUCHL1L3MBTL1
SCHEMBL30292561 0.76 APLNR (0.38) LIPEUCHL1
SCHEMBL1484864 0.76 APLNR (0.38) LIPEUCHL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146513-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed