SCHEMBL580813

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8021598	0.90	NPSR1 (0.79)	ENPP3GAACA2CA9NPSR1
	SCHEMBL7904940	0.86	ENPP3 (0.70)	ENPP3GAANPSR1KDM4ETHRB
	SCHEMBL7913355	0.86	GAA (0.66)	ENPP3GAACA2CA9NPSR1
	SCHEMBL7915165	0.86	ALDH1A1 (0.72)	ENPP3GAANPSR1KDM4ETHRB
	SCHEMBL581896	0.86	GAA (0.91)	ENPP3GAANPSR1KDM4ETHRB
	SCHEMBL7915123	0.86	KDR (0.70)	ENPP3GAACA2CA9NPSR1
	Hydrochloric Acid SCHEMBL580605	0.84	GAA (0.88)	ENPP3GAANPSR1KDM4ETHRB
	SCHEMBL27970830	0.83	ENPP3 (1.00)	ENPP3CA2CA9MAPTPOLB
	SCHEMBL7912113	0.82	KDR (0.72)	ENPP3GAACA9NPSR1KDM4E
	SCHEMBL7915070	0.82	NPSR1 (0.67)	ENPP3GAACA2CA9NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.