Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808195 | 1.00 | MAPT (0.42) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5808252 | 0.91 | PIN1 (0.42) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5808253 | 0.91 | PIN1 (0.42) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5812692 | 0.90 | POLB (0.47) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL5812686 | 0.90 | POLB (0.47) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL5812055 | 0.90 | P2RX3 (0.45) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5807767 | 0.90 | P2RX3 (0.45) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5796248 | 0.81 | TDP1 (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5796244 | 0.81 | TDP1 (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5813909 | 0.80 | PIN1 (0.45) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |