Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.39 |
| ▸ | BAD | Q92934 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808253 | 1.00 | PIN1 (0.42) | PIN1MAPTTP53MCL1BAD | |
| SCHEMBL5807767 | 0.91 | P2RX3 (0.45) | PIN1MAPTTP53MEN1KMT2A | |
| SCHEMBL5812055 | 0.91 | P2RX3 (0.45) | PIN1MAPTTP53MEN1KMT2A | |
| SCHEMBL5808195 | 0.91 | MAPT (0.42) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5808192 | 0.91 | MAPT (0.42) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5813912 | 0.90 | PIN1 (0.45) | PIN1MAPTMCL1BADMEN1 | |
| SCHEMBL5813909 | 0.90 | PIN1 (0.45) | PIN1MAPTMCL1BADMEN1 | |
| SCHEMBL5808367 | 0.87 | PIN1 (0.46) | PIN1MAPTMCL1MEN1KMT2A | |
| SCHEMBL5808364 | 0.87 | PIN1 (0.46) | PIN1MAPTMCL1MEN1KMT2A | |
| SCHEMBL5823777 | 0.82 | PIN1 (0.42) | PIN1MAPTMCL1BADMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |