Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | UGCG | Q16739 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811315 | 0.91 | CNR1 (0.55) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14003135 | 0.77 | HTT (0.52) | LMNAHTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5807932 | 0.74 | UGCG (0.53) | UGCGMEN1KMT2ACNR1CNR2 | |
| SCHEMBL5822464 | 0.74 | CNR2 (0.85) | UGCGCNR1CNR2 | |
| SCHEMBL5808694 | 0.71 | CNR2 (0.68) | UGCGMEN1KMT2ACNR1CNR2 | |
| SCHEMBL5812049 | 0.69 | CNR1 (0.69) | LMNAUGCGALDH1A1CNR1CNR2 | |
| SCHEMBL19554499 | 0.69 | ALDH1A1 (0.54) | LMNAHTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13545818 | 0.69 | DHODH (0.66) | HTTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL342298 | 0.69 | GAA (0.49) | LMNAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL342297 | 0.69 | GAA (0.49) | LMNAUSP2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | claimed |