Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | UGCG | Q16739 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808194 | 0.91 | LMNA (0.54) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14003135 | 0.77 | HTT (0.52) | CNR2TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL5812049 | 0.75 | CNR1 (0.69) | CNR1CNR2ALDH1A1UGCGLMNA | |
| SCHEMBL5811700 | 0.73 | CNR2 (0.61) | CNR1CNR2UGCG | |
| SCHEMBL5806769 | 0.73 | CNR2 (0.96) | CNR1CNR2UGCG | |
| SCHEMBL5811399 | 0.72 | CNR1 (0.65) | CNR1CNR2UGCG | |
| SCHEMBL5808802 | 0.71 | CNR1 (0.56) | CNR1CNR2UGCG | |
| SCHEMBL701934 | 0.70 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HTT | |
| SCHEMBL5811149 | 0.69 | CNR1 (0.59) | CNR1CNR2UGCGCYP1A2CYP2D6 | |
| SCHEMBL16217845 | 0.69 | KMO (0.56) | CNR1CNR2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | claimed |