Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807685 | 0.85 | HTT (0.41) | PDE4DMAPK1LMNAHTTPOLB | |
| SCHEMBL5797163 | 0.84 | PDE4D (0.47) | PDE4DPOLBHPGDHSD17B10NPSR1 | |
| Hydrochloric Acid SCHEMBL5809789 | 0.83 | PDE4D (0.47) | PDE4DPOLBHPGDHSD17B10NPSR1 | |
| SCHEMBL5822481 | 0.81 | ALDH1A1 (0.47) | PDE4DLMNAPOLBGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5812436 | 0.80 | ALDH1A1 (0.46) | PDE4DLMNAPOLBGAAALDH1A1 | |
| SCHEMBL5809786 | 0.77 | PDE4D (0.51) | PDE4DGAAALDH1A1MAPTMEN1 | |
| SCHEMBL3306175 | 0.76 | PDE4D (0.69) | PDE4DLMNAPOLBHPGDHSD17B10 | |
| SCHEMBL1301737 | 0.73 | MAOA (0.43) | PDE4DLMNAHTTCA12CA9 | |
| SCHEMBL5812432 | 0.73 | PDE4D (0.47) | PDE4DMAPK1POLBGAAALDH1A1 | |
| SCHEMBL5016499 | 0.72 | PDE4D (0.46) | PDE4DLMNAHTTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051390-A1 | HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-05-18 | — | — | WO | disclosed |