Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822481 | 0.92 | ALDH1A1 (0.47) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| Hydrochloric Acid SCHEMBL5812436 | 0.91 | ALDH1A1 (0.46) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| SCHEMBL5809786 | 0.86 | PDE4D (0.51) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| SCHEMBL5797163 | 0.78 | PDE4D (0.47) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| Hydrochloric Acid SCHEMBL5809789 | 0.77 | PDE4D (0.47) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| SCHEMBL13620937 | 0.75 | PDE4D (0.46) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| SCHEMBL5808233 | 0.73 | PDE4D (0.44) | PDE4DALDH1A1KMT2AMAPTGAA | |
| SCHEMBL3306175 | 0.70 | PDE4D (0.69) | PDE4DPDE4BALDH1A1PDE4APDE4C | |
| SCHEMBL8268461 | 0.69 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5795878 | 0.69 | PDE4D (0.39) | PDE4DPDE4BALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051390-A1 | HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-05-18 | — | — | WO | disclosed |