Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808243 | 1.00 | P2RX3 (0.42) | P2RX3HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL5823606 | 0.92 | PIN1 (0.40) | P2RX3MCL1PIN1CSNK2A2CSNK2B | |
| SCHEMBL5809988 | 0.89 | SCD (0.46) | HDAC1MCL1MAPTMEN1KMT2A | |
| SCHEMBL5809983 | 0.89 | SCD (0.46) | HDAC1MCL1MAPTMEN1KMT2A | |
| SCHEMBL5799747 | 0.86 | MAPT (0.44) | P2RX3MCL1MAPTMEN1KMT2A | |
| SCHEMBL5799742 | 0.86 | MAPT (0.44) | P2RX3MCL1MAPTMEN1KMT2A | |
| SCHEMBL5798801 | 0.83 | HDAC1 (0.38) | P2RX3HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL5810050 | 0.82 | P2RX3 (0.49) | P2RX3HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL5810052 | 0.82 | P2RX3 (0.49) | P2RX3HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL5797931 | 0.81 | P2RX3 (0.45) | P2RX3HDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |