Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799742 | 1.00 | MAPT (0.44) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5808427 | 0.93 | MAPT (0.48) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5808433 | 0.93 | MAPT (0.48) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5809988 | 0.87 | SCD (0.46) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5809983 | 0.87 | SCD (0.46) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5808246 | 0.86 | P2RX3 (0.42) | MAPTMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL5808243 | 0.86 | P2RX3 (0.42) | MAPTMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL5799796 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5799332 | 0.79 | RAB9A (0.47) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5799330 | 0.79 | RAB9A (0.47) | MAPTMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |