Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808254 | 1.00 | MAOA (0.46) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL6695821 | 0.90 | MAPT (0.55) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL927020 | 0.90 | MAPT (0.55) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL10045756 | 0.90 | MAPT (0.55) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL6769185 | 0.88 | ALDH1A1 (0.55) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6763984 | 0.88 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6769183 | 0.88 | ALDH1A1 (0.55) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6763989 | 0.88 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5464812 | 0.84 | TAAR1 (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5464816 | 0.84 | TAAR1 (0.46) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |