Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769185 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL10045756 | 0.91 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL927020 | 0.91 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6695821 | 0.91 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6763984 | 0.89 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6763989 | 0.89 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5808255 | 0.88 | MAOA (0.46) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5808254 | 0.88 | MAOA (0.46) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5464812 | 0.85 | TAAR1 (0.46) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5464816 | 0.85 | TAAR1 (0.46) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102511-A1 | Substituted pyrrole derivatives | RANBAXY LABORATORIES LIMITED (IN) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102511-A1 | Substituted pyrrole derivatives | HMGCR, PC, CYP46A1 | ALDH1A1 991/4885MEN1 4042/4885KMT2A 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.