Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673658 | 0.79 | HIF1A (0.42) | LMNANPSR1NPC1RAB9APOLB | |
| SCHEMBL5730469 | 0.74 | PTGS2 (0.45) | LMNANPSR1HIF1APTGS2PTGS1 | |
| SCHEMBL2649068 | 0.70 | RAB9A (0.54) | NPC1RAB9APOLBALDH1A1MEN1 | |
| SCHEMBL1566534 | 0.70 | MAPK1 (0.54) | LMNANPC1RAB9AALDH1A1PTGS2 | |
| SCHEMBL3321144 | 0.70 | RAB9A (0.49) | LMNANPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL13407215 | 0.70 | NR4A3 (0.44) | LMNANPSR1NPC1RAB9APOLB | |
| SCHEMBL28600941 | 0.70 | HIF1A (0.41) | LMNANPSR1NPC1RAB9APOLB | |
| SCHEMBL4039361 | 0.70 | MAPT (0.59) | LMNANPSR1NPC1RAB9APOLB | |
| SCHEMBL13019208 | 0.69 | PTGS1 (0.43) | LMNANPSR1POLBALDH1A1PTGS1 | |
| SCHEMBL15330142 | 0.68 | ERN1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033995-A2 | THIAZOLIDIN-4-ONES HAVING ANTI-HEPATITIS B ACTIVITY | VALEANT RESEARCH AND DEVELOPMENT (US) | 2006-03-30 | — | — | WO | disclosed |