Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 15/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.44 |
| ▸ | CA7 | P43166 | 10/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 10/20 | 0.44 |
| ▸ | CA12 | O43570 | 10/20 | 0.44 |
| ▸ | CA9 | Q16790 | 9/20 | 0.44 |
| ▸ | CA4 | P22748 | 8/20 | 0.44 |
| ▸ | CA6 | P23280 | 8/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.44 |
| ▸ | CA3 | P07451 | 6/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 5/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802110 | 0.70 | CA2 (0.59) | CA2CA1CA7CA13CA12 | |
| SCHEMBL11125385 | 0.70 | CA2 (0.45) | CA2CA1CA7CA13CA12 | |
| SCHEMBL2682361 | 0.69 | USP7 (0.58) | — | |
| SCHEMBL1137322 | 0.68 | PTGES2 (0.53) | CA2CA1CA7CA13CA12 | |
| SCHEMBL9262389 | 0.67 | CA2 (0.41) | CA2CA1CA7CA13CA12 | |
| SCHEMBL9828441 | 0.66 | CA2 (0.50) | CA2CA1CA12CA9 | |
| SCHEMBL2345395 | 0.65 | CA2 (0.41) | GUSBCA2CA1CA7CA12 | |
| SCHEMBL7510208 | 0.64 | CA2 (0.58) | CA2CA1CA7CA13CA12 | |
| SCHEMBL5804507 | 0.64 | CA2 (0.49) | CA2CA1CA12CA9 | |
| Diphenylsulfane SCHEMBL9617662 | 0.62 | ALDH1A1 (0.48) | CA2CA1CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006075955-A1 | PYRAZOLYL ACYLSULFONAMIDE DERIVATIVES AS ENDOTHELIN CONVERTING ENZYME INHIBITORS AND USEFUL IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE | ASTRAZENECA AB (SE) | 2006-07-20 | — | — | WO | disclosed |