Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483468 | 0.74 | L3MBTL1 (0.60) | KMT2AMEN1L3MBTL1P2RX4LMNA | |
| SCHEMBL4875253 | 0.73 | KMT2A (0.71) | KMT2AMEN1P2RX4LMNASRC | |
| SCHEMBL4770686 | 0.73 | DCTPP1 (0.51) | KMT2AMEN1P2RX4ALDH1A1 | |
| SCHEMBL4766006 | 0.72 | PDE4A (0.44) | KMT2AMEN1L3MBTL1LMNAPOLB | |
| SCHEMBL4767325 | 0.72 | P2RX3 (0.54) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL29416563 | 0.69 | KMT2A (0.50) | KMT2AMEN1L3MBTL1P2RX4LMNA | |
| SCHEMBL4473737 | 0.69 | P2RX4 (0.47) | KMT2AMEN1L3MBTL1P2RX4LMNA | |
| SCHEMBL4171496 | 0.69 | P2RX4 (0.50) | KMT2AMEN1L3MBTL1P2RX4LMNA | |
| SCHEMBL6510739 | 0.69 | KMT2A (0.72) | KMT2AMEN1P2RX4LMNASRC | |
| SCHEMBL11423863 | 0.69 | KDM4E (0.53) | KMT2AMEN1L3MBTL1P2RX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |