Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820791 | 0.93 | RAB9A (0.62) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6763989 | 0.93 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6763984 | 0.93 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6695821 | 0.83 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL927020 | 0.83 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL10045756 | 0.83 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6769183 | 0.81 | ALDH1A1 (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6769185 | 0.81 | ALDH1A1 (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL2647715 | 0.81 | MEN1 (0.49) | MAPTMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2647713 | 0.81 | MEN1 (0.49) | MAPTMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |