Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805083 | 0.90 | EGFR (0.47) | MAPTUBE2NMEN1KMT2ATDP1 | |
| SCHEMBL5804950 | 0.85 | KDR (0.42) | MAPTUBE2NGAAEGFRKDR | |
| SCHEMBL4169210 | 0.85 | HMGCR (0.47) | MAPTUBE2NMEN1KMT2AKDM4E | |
| SCHEMBL5807727 | 0.84 | HMGCR (0.46) | MAPTUBE2NMEN1KMT2AKDM4E | |
| SCHEMBL5804872 | 0.83 | RAB9A (0.46) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL5808355 | 0.83 | KCNK9 (0.43) | MAPTUBE2NNPSR1KDM4EGAA | |
| SCHEMBL5805311 | 0.83 | HTT (0.45) | MAPTUBE2NALDH1A1EGFRKDR | |
| SCHEMBL5808861 | 0.83 | HTT (0.45) | MAPTUBE2NALDH1A1EGFRKDR | |
| SCHEMBL5806885 | 0.80 | CHEK1 (0.42) | MAPTUBE2NALDH1A1KDM4EATR | |
| SCHEMBL5806553 | 0.80 | HMGCR (0.43) | MAPTMEN1KMT2ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | claimed |
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |