SCHEMBL5809344

SCHEMBL5809344

C=C(C#N)C(=O)Oc1ccccc1-c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
GAA P10253 2/20 0.41
PGR P06401 1/20 0.41
PTGS1 P23219 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 1/20 0.40
POLB P06746 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
BCHE P06276 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5808449 0.89 HSD17B10 (0.51) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL5809352 0.83 CYP2C9 (0.54) CYP1A2CYP2C9CYP2C19HDAC8HDAC6
SCHEMBL28421323 0.82 ALDH1A1 (0.46) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10
SCHEMBL11672675 0.79 ALDH1A1 (0.41) CYP1A2CYP2C19ALDH1A1HSD17B10GAA
SCHEMBL2291363 0.79 ALDH1A1 (0.49) CYP2C9CYP2C19ALDH1A1HSD17B10GAA
SCHEMBL2291368 0.78 ALDH1A1 (0.49) CYP2C9CYP2C19ALDH1A1HSD17B10GAA
SCHEMBL1156687 0.78 ALDH1A1 (0.47) CYP2C9CYP2C19ALDH1A1HSD17B10GAA
SCHEMBL1156690 0.76 ALDH1A1 (0.47) CYP2C9CYP2C19ALDH1A1HSD17B10GAA
SCHEMBL10806722 0.76 GSK3B (0.56) CYP1A2CYP2C9ALDH1A1HSD17B10GAA
SCHEMBL2111828 0.76 TYMS (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006110301-A2 PHOTOABSORBING, HIGHLY CONJUGATED COMPOUNDS OF CYANOACRYLIC ESTERS, SUNSCREEN COMPOSITIONS AND METHODS OF USE CPH INNOVATIONS CORP. (US) 2006-10-19 WO disclosed