Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919293 | 0.87 | MAPT (0.60) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL1919926 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL1919396 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL23851985 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL1920134 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL1624009 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL29409508 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL13374135 | 0.73 | LMNA (0.39) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL12763840 | 0.73 | KIF11 (0.42) | KDM4EMAPTLMNA | |
| SCHEMBL15110858 | 0.73 | MAPT (0.61) | KDM4EALDH1A1L3MBTL1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |