SCHEMBL5809748

SCHEMBL5809748

Cc1[nH]c2c(OCc3ccc(F)cc3)nccc2c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
MPO P05164 1/20 0.40
MAOA P21397 3/20 0.38
HTR6 P50406 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2D6 P10635 1/20 0.36
ACHE P22303 1/20 0.36
MAOB P27338 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CCNB2 O95067 1/20 0.36
CDK1 P06493 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5811001 0.99 CNR1 (0.39) CNR1CNR2CYP1A2CYP3A4CYP2C9
SCHEMBL5806648 0.88 CYP1A2 (0.39) CYP1A2CYP3A4CYP2C9CYP2C19MAOA
Hydrochloric Acid SCHEMBL5806824 0.87 CYP1A2 (0.38) CYP1A2CYP3A4CYP2C9CYP2C19MAOA
SCHEMBL5808896 0.86 HTR6 (0.50) CYP1A2CYP3A4CYP2C9CYP2C19MAOA
SCHEMBL5811682 0.86 MAOA (0.47) CYP1A2CYP3A4CYP2C9CYP2C19MPO
SCHEMBL5807542 0.85 HTR6 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19MPO
SCHEMBL5811668 0.83 CYP1A2 (0.41) CNR1CNR2CYP1A2CYP3A4CYP2C9
SCHEMBL5808715 0.82 CYP1A2 (0.40) CYP1A2CYP3A4CYP2C9CYP2C19MAOA
SCHEMBL7480371 0.82 CYP1A2 (0.49) CNR1CNR2CYP1A2CYP3A4CYP2C9
SCHEMBL5811394 0.81 TRPA1 (0.49) CYP1A2CYP3A4CYP2C9CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed