Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222577 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDRXFP1PRKAB2 | |
| SCHEMBL13993008 | 0.84 | PRKAB2 (0.36) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL5794998 | 0.81 | DRD2 (0.46) | KDM4EALDH1A1HPGDPRKAB2PRKAG1 | |
| SCHEMBL15758912 | 0.81 | PRKAB2 (0.48) | KDM4EALDH1A1HPGDRXFP1PRKAB2 | |
| SCHEMBL4221938 | 0.80 | PRKAB2 (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL15758209 | 0.79 | AQP1 (0.39) | KDM4EALDH1A1HPGDRXFP1PRKAB2 | |
| SCHEMBL14047097 | 0.79 | PRKAB2 (0.41) | KDM4EALDH1A1HPGDRXFP1PRKAB2 | |
| SCHEMBL4596960 | 0.79 | HPGD (0.56) | KDM4EALDH1A1HPGDPRKAB2PRKAG1 | |
| SCHEMBL4221927 | 0.79 | AQP1 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL8269776 | 0.79 | PRKAB2 (0.36) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000902-A1 | DIHYDROBENZOFURAN COMPOUNDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |