Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797711 | 1.00 | HTR1D (0.50) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL5797651 | 0.91 | HTR1D (0.47) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL5810882 | 0.91 | HTR1D (0.47) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL5795711 | 0.91 | P2RX3 (0.57) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL1306899 | 0.81 | CYP1A2 (0.42) | MRGPRX4P2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1305730 | 0.80 | MAPT (0.39) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL1305732 | 0.80 | MAPT (0.39) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL3819413 | 0.80 | P2RX3 (0.45) | HTR1DHTR1BMRGPRX4P2RX3ALDH1A1 | |
| SCHEMBL1306931 | 0.77 | P2RX3 (0.39) | HTR1BMRGPRX4P2RX3ALDH1A1KDM4E | |
| SCHEMBL1306759 | 0.77 | P2RX3 (0.39) | HTR1BMRGPRX4P2RX3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |