Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797651 | 1.00 | HTR1D (0.47) | HTR1DHTR1BP2RX3KDM4EALDH1A1 | |
| SCHEMBL5810743 | 0.91 | HTR1D (0.50) | HTR1DHTR1BP2RX3KDM4EALDH1A1 | |
| SCHEMBL5797711 | 0.91 | HTR1D (0.50) | HTR1DHTR1BP2RX3KDM4EALDH1A1 | |
| SCHEMBL5795711 | 0.90 | P2RX3 (0.57) | HTR1DHTR1BP2RX3KDM4EALDH1A1 | |
| SCHEMBL12113452 | 0.84 | ALDH1A1 (0.49) | P2RX3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1306778 | 0.84 | ALDH1A1 (0.49) | P2RX3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1306780 | 0.84 | ALDH1A1 (0.49) | P2RX3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12113454 | 0.82 | ALDH1A1 (0.47) | P2RX3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1306406 | 0.82 | ALDH1A1 (0.47) | P2RX3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1306405 | 0.82 | ALDH1A1 (0.47) | P2RX3KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |