Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810743 | 0.91 | HTR1D (0.50) | P2RX3HTR1DHTR1BALDH1A1MAPT | |
| SCHEMBL5797711 | 0.91 | HTR1D (0.50) | P2RX3HTR1DHTR1BALDH1A1MAPT | |
| SCHEMBL5797651 | 0.90 | HTR1D (0.47) | P2RX3HTR1DHTR1BALDH1A1MAPT | |
| SCHEMBL5810882 | 0.90 | HTR1D (0.47) | P2RX3HTR1DHTR1BALDH1A1MAPT | |
| SCHEMBL3820610 | 0.81 | P2RX3 (0.51) | P2RX3HDAC6HDAC1ALDH1A1MAPT | |
| SCHEMBL1305152 | 0.81 | P2RX3 (0.49) | P2RX3HDAC6HDAC1ALDH1A1MAPT | |
| SCHEMBL3811300 | 0.81 | P2RX3 (0.55) | P2RX3HDAC6HDAC1ALDH1A1MAPT | |
| SCHEMBL5807650 | 0.79 | P2RX3 (0.48) | P2RX3HTR1DHTR1BHDAC6HDAC1 | |
| SCHEMBL5807646 | 0.79 | P2RX3 (0.48) | P2RX3HTR1DHTR1BHDAC6HDAC1 | |
| SCHEMBL1306879 | 0.77 | P2RX3 (0.57) | P2RX3HTR1DHTR1BHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |