Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928793 | 0.87 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL28799328 | 0.83 | PTGS1 (0.62) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL4363732 | 0.81 | MEN1 (0.89) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL30739691 | 0.80 | KMT2A (0.68) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL9343198 | 0.79 | KMT2A (0.66) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL31388520 | 0.78 | ALB (0.57) | ALDH1A1P2RX1P2RX7HPGDKDM4E | |
| SCHEMBL1259459 | 0.78 | ALB (0.57) | ALDH1A1P2RX1P2RX7HPGDKDM4E | |
| SCHEMBL28995015 | 0.78 | KMT2A (0.64) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL8535595 | 0.77 | KCNK3 (0.62) | KMT2AKCNK3KCNK9HPGDRXFP1 | |
| SCHEMBL22820183 | 0.77 | NPC1 (0.67) | MEN1KMT2ANPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086229-A1 | THE USE OF SELECTIVE P2X7 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2006-08-17 | — | — | WO | disclosed |