Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700361 | 0.84 | NPC1 (0.71) | NPC1RAB9APTGS1SMN1; SMN2RXFP1 | |
| SCHEMBL22819939 | 0.84 | LMNA (0.70) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL22819966 | 0.82 | ALDH1A1 (0.70) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL22820200 | 0.81 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL2698258 | 0.81 | P2RX1 (0.75) | NPC1RAB9APTGS1SMN1; SMN2LMNA | |
| SCHEMBL2638776 | 0.81 | PTGS1 (0.70) | NPC1RAB9APTGS1SMN1; SMN2RXFP1 | |
| SCHEMBL30665186 | 0.81 | P2RX1 (0.75) | NPC1RAB9APTGS1SMN1; SMN2LMNA | |
| SCHEMBL31393757 | 0.81 | CHRNB2 (0.71) | NPC1RAB9APTGS1SMN1; SMN2 | |
| SCHEMBL2564890 | 0.80 | NPC1 (1.00) | NPC1RAB9APTGS1LMNAP2RX1 | |
| SCHEMBL4247052 | 0.80 | NPC1 (0.86) | NPC1RAB9APTGS1LMNAP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |