Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811120 | 0.91 | ADORA3 (0.40) | HTR1AADORA2AALDH1A1APOBEC3GFABP3 | |
| SCHEMBL5807295 | 0.86 | MAPK11 (0.44) | MAPTALDH1A1LMNAMAPK13CYP2C9 | |
| SCHEMBL5812295 | 0.81 | MAPK13 (0.53) | MAPTALDH1A1MAPK13CYP2C9MAPK11 | |
| SCHEMBL5808593 | 0.75 | MAPK11 (0.44) | MAPTALDH1A1MAPK13CYP2C9MAPK11 | |
| SCHEMBL5806880 | 0.72 | MAPK13 (0.50) | ADORA2AMAPTALDH1A1LMNAMAPK13 | |
| SCHEMBL5811997 | 0.72 | MAPK11 (0.57) | MAPK13CYP2C9MAPK11 | |
| Bromide SCHEMBL5806494 | 0.72 | CYP1A2 (0.50) | ADORA2AMAPTALDH1A1LMNACYP2C9 | |
| SCHEMBL4246294 | 0.72 | MAPK11 (0.55) | MAPTALDH1A1MAPK13CYP2C9MAPK11 | |
| SCHEMBL4246031 | 0.72 | MAPK13 (0.49) | MAPTALDH1A1FABP4MAPK13CYP2C9 | |
| SCHEMBL4243633 | 0.71 | MAPK13 (0.49) | MAPTALDH1A1MAPK13CYP2C9MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |