Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.39 |
| ▸ | RORB | Q92753 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819107 | 0.88 | ADORA2A (0.38) | ADORA2AADORA1KMOADORA2BDPP4 | |
| SCHEMBL5813644 | 0.82 | CCNT1 (0.47) | ADORA2AADORA1TGFBR1KMOPLK1 | |
| SCHEMBL5817990 | 0.82 | PTGDR2 (0.36) | ADORA2AADORA1TGFBR1MAPK14 | |
| SCHEMBL5821649 | 0.80 | ADORA2A (0.39) | ADORA2AADORA1DPP4CYP19A1MAPK14 | |
| SCHEMBL5819868 | 0.78 | CDC7 (0.38) | ADORA2AADORA1TGFBR1DPP4PIM1 | |
| SCHEMBL5820844 | 0.77 | KCNH2 (0.41) | TGFBR1MAPK14 | |
| SCHEMBL5820628 | 0.77 | KCNH2 (0.46) | — | |
| SCHEMBL5818662 | 0.76 | KCNH2 (0.44) | MAPK14 | |
| SCHEMBL5818860 | 0.76 | LMNA (0.44) | ADORA2AADORA1RORBTGFBR1KMO | |
| SCHEMBL5812491 | 0.76 | CAMK2D (0.47) | PLK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |