Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839998 | 0.79 | KDM1A (0.31) | KDM1A | |
| SCHEMBL28941422 | 0.78 | CTSK (0.33) | CTSK | |
| SCHEMBL8521331 | 0.75 | CTSK (0.35) | CTSK | |
| SCHEMBL7776733 | 0.75 | KDM1A (0.37) | KDM1A | |
| SCHEMBL3676865 | 0.75 | — | — | |
| SCHEMBL3674606 | 0.73 | KDM1A (0.35) | KDM1A | |
| SCHEMBL3674602 | 0.73 | KDM1A (0.35) | KDM1A | |
| SCHEMBL3526537 | 0.71 | — | — | |
| SCHEMBL14434894 | 0.71 | — | — | |
| SCHEMBL23959792 | 0.71 | CTSK (0.36) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115748-B2 | Method of making imidazole-2-thiones | ALLERGAN, INC. (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2006062890-A1 | METHOD OF MAKING IMIDAZOLE-2-THIONES | ALLERGAN, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122400-A1 | Method of making imidazole-2-thiones | ALLERGAN, INC. | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122400-A1 | Method of making imidazole-2-thiones | TST, INMT, TPMT | CTSK 3242/4885KDM1A 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.