Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 9/20 | 0.73 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680061 | 1.00 | STS (0.73) | STSPPARGCA1CA2HPGD | |
| SCHEMBL28512992 | 0.85 | STS (0.76) | STSPPARGHPGDRECQLESR1 | |
| SCHEMBL17129831 | 0.85 | STS (0.71) | STSPPARGCA1CA2HPGD | |
| SCHEMBL14720856 | 0.82 | STS (0.68) | STSPPARGCA1CA2HPGD | |
| SCHEMBL87450 | 0.81 | CA1 (0.83) | STSCA1CA2HPGDCA12 | |
| SCHEMBL11713918 | 0.81 | STS (0.66) | STSPPARGCA1CA2HPGD | |
| SCHEMBL3626199 | 0.81 | CA2 (0.51) | STSCA1CA2HPGDCA12 | |
| SCHEMBL980002 | 0.80 | STS (0.71) | STSCA1CA2HPGDCA12 | |
| SCHEMBL581359 | 0.80 | KMT2A (0.65) | STSPPARGCA1CA2CA12 | |
| SCHEMBL1962850 | 0.80 | TDP1 (0.60) | STSCA1CA2HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2660249-B1 | PEPTIDE DERIVATIVE AND USE THEREOF | UNIV KYOTO (JP) | 2019-07-10 | — | — | EP | disclosed |
| EP-2484386-B1 | MOLECULAR PROBE FOR PANCREATIC ISLETS IMAGING AND USE OF SAID PROBE | UNIV KYOTO (JP) | 2019-04-17 | — | — | EP | disclosed |
| EP-2510951-B1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET, AND USE THEREOF | UNIV KYOTO (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-9278146-B2 | Peptide derivative and use of the same | KYOTO UNIVERSITY (JP) | 2016-03-08 | — | — | US | disclosed |
| US-9238083-B2 | Molecular probe for imaging of pancreatic islets and use of the same | KYOTO UNIVERSITY (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2418216-B1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND PRECURSOR THEREOF, AND USE OF THE MOLECULAR PROBE OR THE PRECURSOR | UNIV KYOTO (JP) | 2015-10-28 | — | — | EP | disclosed |
| CN-102282164-B | Pancreas islet imaging molecular probe and precursor thereof, and their use | KYOTO UNIVERSITY (JP) | 2015-09-16 | — | — | CN | disclosed |
| US-20150231284-A1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME | ARKRAY, INC. (JP) | 2015-08-20 | — | — | US | disclosed |
| US-8980220-B2 | Molecular probe for imaging of pancreatic islets and use of the same | KYOTO UNIVERSITY (JP) | 2015-03-17 | — | — | US | disclosed |
| CN-102596259-B | Molecular probe for pancreatic islet imaging and use of said probe | UNIV KYOTO | 2015-03-11 | — | — | CN | disclosed |
| EP-2314581-B1 | A process for preparing benzo[b]thiophene derivatives | HEXAL AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| CN-102596259-A | Molecular probe for pancreatic islet imaging and use of said probe | UNIV KYOTO | 2012-07-18 | — | — | CN | disclosed |
| US-20120087863-A1 | Peptide Derivative and Use of the Same | ARKRAY, INC. (JP) | 2012-04-12 | — | — | US | disclosed |
| EP-2418216-A1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND PRECURSOR THEREOF, AND USE OF THE MOLECULAR PROBE OR THE PRECURSOR | Kyoto University (JP) | 2012-02-15 | — | — | EP | disclosed |
| CN-102282164-A | Molecular probe for imaging of pancreatic islet and precursor thereof, and use of the molecular probe or the precursor | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| WO-2011047877-A1 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314581-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-04-27 | — | — | EP | disclosed |
| US-20110081663-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-04-07 | — | — | US | disclosed |
| US-20110033381-A1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME | KYOTO UNIVERSITY (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, NGLY1, GPR119 | STS 4705/4885PPARG 2085/4885CA1 1477/4885 |
| US-20120087863-A1 | Peptide Derivative and Use of the Same | VIP, IAPP, GLP1R | STS 3881/4885PPARG 1571/4885CA1 2423/4885 |
| US-20150231284-A1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME | IAPP, PDXK, NLK | STS 2724/4885PPARG 3413/4885CA1 1811/4885 |
| US-20110033381-A1 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME | IAPP, PDXK, NLK | STS 2280/4885PPARG 3986/4885CA1 1760/4885 |
| US-20110081663-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, GPR119, NPY1R | STS 4336/4885PPARG 476/4885CA1 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.