SCHEMBL5813046

SCHEMBL5813046

NC(=O)[C@@H](O)C[C@H](N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.52
▸ SLC1A1 P43005 4/20 0.48
▸ SLC1A3 P43003 4/20 0.46
▸ SLC1A2 P43004 4/20 0.46
▸ GRIK1 P39086 5/20 0.45
▸ GRIK2 Q13002 5/20 0.45
▸ ALOX15 P16050 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ PMP22 Q01453 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ PTGS1 P23219 1/20 0.44
▸ SLC7A11 Q9UPY5 1/20 0.44
▸ GGT1 P19440 2/20 0.43
▸ GRM1 Q13255 1/20 0.43
▸ GRM2 Q14416 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1512926 1.00 SLC7A5 (0.52) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL1512928 1.00 SLC7A5 (0.52) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL8420686 1.00 SLC7A5 (0.52) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL1607862 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL196983 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL13746293 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL5819946 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL5823952 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL13753646 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1
SCHEMBL305904 0.84 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884390-B1 Method for producing an optically active compound KYOWA HAKKO KOGYO KK (JP) 2006-05-10 — — EP claimed
US-20020006645-A1 Method for producing optically active compound HASHIMOTO SHIN-ICHI (JP) 2002-01-17 — — US claimed
US-6207427-B1 ALLOWING RECOMBINANT MICROORGANISM CARRYING RECOMBINANT DNA HARBORING (S)-4-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE GENE TO ACT ON SUGAR AND GLYOXYLIC ACID IN AN AQUEOUS MEDIUM, AND COLLECTING OPTICALLY ACTIVE (S)-4-HYDROXY-2-KETOGLUTARIC ACID KYOWA HAKKO KOGYO, LTD. (JP) 2001-03-27 — — US claimed
EP-0692539-B1 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO KK (JP) 1999-09-22 — — EP claimed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 — — EP claimed
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2026-01-29 — — US disclosed
US-12410213-B2 Polypeptides self-assembling into nanoparticles ETH ZËRICH (CH) 2025-09-09 — — US disclosed
EP-3833676-B1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2025-05-28 — — EP disclosed
CN-112533938-B Polypeptides self-assembled into nanoparticles 苏黎世联邦理工学院 2025-04-25 — — CN disclosed
EP-4103160-B1 NANOPARTICLES ENCAPSULATING SMALL MOLECULES ETH ZUERICH (CH) 2024-06-26 — — EP disclosed
US-20230080270-A1 NANOPARTICLES ENCAPSULATING SMALL MOLECULES ETH ZURICH (CH) 2023-03-16 — — US disclosed
EP-4103160-A1 NANOPARTICLES ENCAPSULATING SMALL MOLECULES ETH Zurich (CH) 2022-12-21 — — EP disclosed
CN-112533938-A Polypeptides that self-assemble into nanoparticles 苏黎世联邦理工学院 2021-03-19 — — CN disclosed
WO-2020030654-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH Zürich (CH) 2020-02-13 — — WO disclosed
US-20150064714-A1 Polypeptides containing a modified fragment of the peptide IF1 LIFESEARCH (FR) 2015-03-05 — — US disclosed
EP-0884390-B1 Method for producing an optically active compound KYOWA HAKKO KOGYO KK (JP) 2006-05-10 — — EP disclosed
US-6365381-B2 PRODUCING (S)-4-HYDROXY-2-KETOGLUTARIC ACID AND COMPOUNDS WHICH ARE FORMED BY BIOSYNTHESIS FROM THIS PRECURSOR USING RECOMBINANT MICROORGANISM CARRYING A RECOMBINANT DNA HARBORING THIS ACID ALDOLASE GENE, SUGAR AND GLYOXYLIC ACID KYOWA HAKKO KOGYO, LTD. (JP) 2002-04-02 — — US disclosed
US-20020006645-A1 Method for producing optically active compound HASHIMOTO SHIN-ICHI (JP) 2002-01-17 — — US disclosed
US-6207427-B1 ALLOWING RECOMBINANT MICROORGANISM CARRYING RECOMBINANT DNA HARBORING (S)-4-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE GENE TO ACT ON SUGAR AND GLYOXYLIC ACID IN AN AQUEOUS MEDIUM, AND COLLECTING OPTICALLY ACTIVE (S)-4-HYDROXY-2-KETOGLUTARIC ACID KYOWA HAKKO KOGYO, LTD. (JP) 2001-03-27 — — US disclosed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES PHAX, TPX2, MLX SLC7A5 192/4885SLC1A1 223/4885SLC1A3 205/4885
US-20150064714-A1 Polypeptides containing a modified fragment of the peptide IF1 NGLY1, TAP1, F13A1 SLC7A5 3253/4885SLC1A1 1325/4885SLC1A3 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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