Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477924 | 0.82 | NCF1 (0.47) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL5210878 | 0.82 | HRH4 (0.34) | CHIA | |
| SCHEMBL5932074 | 0.82 | ELANE (0.43) | CXCR4CHIA | |
| SCHEMBL4477563 | 0.75 | ALDH1A1 (0.44) | CYP2D6 | |
| SCHEMBL5611262 | 0.75 | NCF1 (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1737562 | 0.75 | NCF1 (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL4732267 | 0.75 | NCF1 (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL5808116 | 0.74 | FPR2 (0.38) | CXCR4DRD2DRD3KMT2A | |
| SCHEMBL5166529 | 0.74 | CHIA (0.43) | CHIA | |
| SCHEMBL4467894 | 0.74 | PTGER3 (0.41) | HTR1ADRD2DRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |