Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813336 | 1.00 | GAA (0.45) | GAAKMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5808726 | 0.90 | GAA (0.44) | GAAKMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5808727 | 0.90 | GAA (0.44) | GAAKMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5808190 | 0.84 | GAA (0.45) | GAAKMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5799115 | 0.80 | POLB (0.59) | GAAALDH1A1HSD17B10 | |
| SCHEMBL5799117 | 0.80 | POLB (0.59) | GAAALDH1A1HSD17B10 | |
| SCHEMBL5822676 | 0.77 | FAAH (0.41) | GAAKMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5799786 | 0.74 | SMN1; SMN2 (0.45) | HPGDALDH1A1TSHR | |
| SCHEMBL13318220 | 0.71 | ALDH1A1 (0.72) | GAAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL5807113 | 0.70 | POLB (0.58) | GAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |