Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821122 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5795985 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5795629 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HPGDRAB9AHTT | |
| SCHEMBL5821186 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDRAB9AHTT | |
| SCHEMBL5821639 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDRAB9AHTT | |
| SCHEMBL5798794 | 0.79 | NQO2 (0.40) | SMN1; SMN2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5799042 | 0.77 | FAAH (0.44) | SMN1; SMN2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL22042582 | 0.75 | RAB9A (0.57) | SMN1; SMN2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5799117 | 0.74 | POLB (0.59) | SMN1; SMN2ALDH1A1NPC1HTTMAPT | |
| SCHEMBL5799115 | 0.74 | POLB (0.59) | SMN1; SMN2ALDH1A1NPC1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |