SCHEMBL58137

SCHEMBL58137

c1cnc2c(c1)ccc1sccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
KDM4E B2RXH2 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
MAPT P10636 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL17242046 0.91 PARP1 (0.47) LMNACCR1CCR5CCR8KDM4E
SCHEMBL2906317 0.81 LMNA (0.43) LMNACCR1CCR5CCR8KDM4E
SCHEMBL22013890 0.80 LMNA (0.47) LMNACCR1CCR5CCR8KDM4E
SCHEMBL1246514 0.75 CCR1 (0.75) LMNACCR1CCR5CCR8KDM4E
SCHEMBL5004845 0.75 CCR1 (0.50) LMNACCR1CCR5CCR8KDM4E
Phenanthroline SCHEMBL2355221 0.75 CCR1 (0.94) LMNACCR1CCR5CCR8KDM4E
SCHEMBL7289957 0.74 HTR2C (0.33) LMNAKDM4EMAPT
SCHEMBL23218293 0.73 KDM4E (0.58) LMNACCR1CCR5CCR8KDM4E
SCHEMBL9533808 0.73 KDM4E (0.38) LMNAKDM4EMAPTHTTTDP1
SCHEMBL2049452 0.73 HTR2C (0.35) LMNAKDM4EMAPTHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185329-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 EP claimed
EP-3185328-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-05-22 EP claimed
EP-3185332-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-05-01 EP claimed
EP-3185330-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-08-16 EP claimed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US claimed
US-10164195-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-12-25 US claimed
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 EP claimed
EP-3185332-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP claimed
EP-3185328-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP claimed
EP-3185329-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP claimed
US-20170179416-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US claimed
US-20170179396-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US claimed
US-20170179397-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US claimed
US-20170179395-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US claimed
US-8212048-B2 Method of producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US claimed
US-8129365-B2 Water-soluble, fluorescent compounds for detection of potassium ions THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-03-06 US claimed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP claimed
US-20080311041-A1 Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-12-18 US claimed
WO-2007044866-A2 WATER-SOLUBLE, FLUORESCENT COMPOUNDS FOR DETECTION OF POTASSIUM IONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-04-19 WO claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311041-A1 Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions TACR2, KCNJ8, TAC3 LMNA 2145/4885CCR1 1671/4885CCR5 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.