Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814637 | 1.00 | AKR1C3 (0.41) | AKR1C3AKR1C2LMNAELANEPTGS2 | |
| SCHEMBL5797770 | 0.90 | LMNA (0.41) | AKR1C3AKR1C2LMNAELANEPTGS2 | |
| SCHEMBL5797826 | 0.90 | LMNA (0.47) | AKR1C3AKR1C2LMNAELANEPTGS2 | |
| SCHEMBL5797827 | 0.90 | LMNA (0.47) | AKR1C3AKR1C2LMNAELANEPTGS2 | |
| SCHEMBL5808091 | 0.89 | AKR1C3 (0.42) | AKR1C3AKR1C2LMNAELANEPTGS2 | |
| SCHEMBL5797008 | 0.88 | PTGS2 (0.44) | ELANEPTGS2PTGS1 | |
| SCHEMBL5797009 | 0.88 | PTGS2 (0.44) | ELANEPTGS2PTGS1 | |
| SCHEMBL5560396 | 0.87 | AKR1C3 (0.45) | AKR1C3AKR1C2LMNAPTGS2PTGS1 | |
| SCHEMBL5550600 | 0.87 | AKR1C3 (0.45) | AKR1C3AKR1C2LMNAPTGS2PTGS1 | |
| SCHEMBL5555009 | 0.87 | AKR1C3 (0.45) | AKR1C3AKR1C2LMNAPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |