Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19472000 | 0.82 | CYP19A1 (0.78) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL8580709 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| Piperonal SCHEMBL1864802 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL5814905 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| Piperonal SCHEMBL29318 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| Piperonal SCHEMBL29411164 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL1987675 | 0.78 | CYP3A4 (0.71) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL5911216 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL29399800 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1HSD17B10CYP3A4ATM | |
| SCHEMBL11774250 | 0.77 | GRIN2D (0.70) | ALDH1A1TDP1HSD17B10CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180031738-A1 | RETARDATION PLATE AND CIRCULARLY POLARIZING PLATE | DIC CORPORATION (JP) | 2018-02-01 | — | — | US | disclosed |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20180016502-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC CORPORATION (JP) | 2018-01-18 | — | — | US | disclosed |
| WO-2015129755-A1 | NOVEL COMPOUND AND TEXTURE IMPROVER CONTAINING SAID COMPOUND | 味の素株式会社 | 2015-09-03 | — | — | WO | disclosed |
| US-20130289022-A1 | TETRAMERIC ALPHA-SYNUCLEIN AND USE THEREOF | BRANDEIS UNIVERSITY (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2008019690-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2008-02-21 | — | — | WO | disclosed |
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | KALYPSYS, INC. | 2006-11-09 | — | — | US | disclosed |
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | MAPK1, MAP3K1, MAPK4 | ALDH1A1 4346/4885TDP1 583/4885HSD17B10 3844/4885 |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | SMC4, MAP1LC3C, ZW10 | ALDH1A1 3195/4885TDP1 2599/4885HSD17B10 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.