Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709769 | 0.88 | MAPT (0.36) | RAB9AMEN1KMT2ACES1AKR1C3 | |
| SCHEMBL5937851 | 0.82 | CES2 (0.52) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL14199227 | 0.82 | CES2 (0.52) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL24060995 | 0.80 | CES2 (0.50) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL21626552 | 0.80 | CES2 (0.50) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL21146559 | 0.76 | CES2 (0.46) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL2146885 | 0.76 | CYP2C19 (0.47) | MEN1KMT2ACES2CES1LMNA | |
| SCHEMBL29268252 | 0.76 | CYP2C19 (0.47) | MEN1KMT2ACES2CES1LMNA | |
| SCHEMBL8105552 | 0.76 | CYP2C19 (0.47) | MEN1KMT2ACES2CES1LMNA | |
| SCHEMBL7147096 | 0.75 | TSHR (0.48) | CES2CES1LMNACYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109068-B1 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and processing cartridge | KONISHIROKU PHOTO IND (JP) | 2006-02-22 | — | — | EP | disclosed |
| EP-1109068-A2 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and processing cartridge | KONICA CORPORATION (JP) | 2001-06-20 | — | — | EP | disclosed |