Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821754 | 0.90 | SCD (0.53) | SCDKDM4ESMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL5821745 | 0.87 | SCD (0.42) | SCDSMN1; SMN2HCRTR1HCRTR2HTT | |
| SCHEMBL5820149 | 0.86 | SCD (0.43) | SCDKDM4ESMN1; SMN2LMNAHCRTR1 | |
| SCHEMBL5816171 | 0.85 | SCD (0.47) | SCDKDM4ESMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL5821535 | 0.84 | SCD (0.42) | SCDSMN1; SMN2LMNAHCRTR1HCRTR2 | |
| SCHEMBL5821224 | 0.82 | SCD (0.46) | SCDKDM4ESMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL27712785 | 0.77 | HCRTR1 (0.46) | SCDHCRTR1HCRTR2PARP1 | |
| SCHEMBL5821749 | 0.77 | ALDH1A1 (0.53) | HTR1A | |
| SCHEMBL5821701 | 0.76 | SCD (0.54) | SCDLMNA | |
| SCHEMBL5818472 | 0.75 | SCD (0.58) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125180-A1 | PIPERAZINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |